Preheat your oven to 375F and grease a 9x5-inch loaf pan. You can also line a pan with parchment paper that hangs over the edges, to make it easy to remove the meatloaf.
In a large bowl, add all of the meatloaf ingredients except the ground beef, and mix with a spoon.
Add the ground beef to the bowl and use your hands to mix everything together.
Transfer the meat to the loaf pan and smooth the top into an even layer.
Add all of the sauce ingredients to a mixing bowl (it can be the same bowl you used earlier) and whisk to combine.
Spread the sauce over the top of the meatloaf.
Bake the meatloaf in the center rack of the oven for 60-70 minutes, or until the internal temperature reaches 165F.
Cool the meatloaf on a wire rack for 15-20 minutes before slicing and serving. This will allow the meatloaf to firm up so it stays in one piece when slice it.
Notes
Store leftovers in an airtight container in the fridge for 4 days, or in the freezer for 6 months.
To reheat, add slices of meatloaf to a baking dish, and drizzle with beef or chicken broth. Cover with aluminum foil and heat in a 250F oven for 20 minutes.
The meat amount is not exact. It's totally fine if you have a little more or a little less than 2 pounds.
Lean beef will fall apart a little more easily than regular ground beef, but both work great.